Nitazoxanide as a New Local Adjunctive to Nonsurgical Treatment of Moderate Periodontitis

• Status: Completed
• Trial end date: 2020-04-30
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study was to assess the effect of nitazoxanide delivered subgingivally as thermosensitive hydrogel on the clinical and biochemical outcomes of SRP in patients with moderate periodontitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maha Talaab
• Treatments: Nitazoxanide

Criteria

Inclusion Criteria:

• Patients having probing depth (PD) ≥5 mm.

• Patients having bleeding on probing (BOP) in proximal tooth surface.

• Patients who could maintain an O'Leary plaque index ≤10 proceeded into the study.

Exclusion Criteria:

• Patients having any systemic disease that may affect the treatment outcomes.

• Smokers.

• Pregnant females.

• Patients receiving contraindicated medications, chemotherapy, or radiotherapy in the previous year.