Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)

• Status: Enrolling by invitation
• Trial end date: 2021-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Cardiovascular disease is the leading cause of death in the United States. Other studies have shown that stress, early in life, could be a risk factor for cardiovascular disease, later in life. This study will look at the effect of early life stressors on your cardiovascular health.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Augusta University
• Collaborator: National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Antioxidants; Ascorbic Acid; Nitric Oxide; Nitroglycerin; Polystyrene sulfonic acid; Thioctic Acid; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

• documented childhood SES

• men and premenopausal women ages 18-40

• lean/overweight/or obese with BMI< or equal to 39kg/m2

Exclusion Criteria:

• cardiovascular, renal, pulmonary, hepatic, cerebral, or metabolic,disease

• use medications that affect vascular tone

• post menopausal women

• have class 3 obesity or BMI over 40