Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes
Status:
Completed
Trial end date:
2019-05-01
Target enrollment:
Participant gender:
Summary
The study aims to evaluate and assess the effectiveness and safety of vaginal administration
of isosorbide mono nitrate (IMN) to induce cervical ripening and shorten the interval time
between induction and delivery in women undergoing induction of labor at term or post term
with prelabor rupture of membrane.
Research Hypothesis:
In women undergoing induction of labor at term or post term with pre-labor rupture of
membrane, vaginal administration of isosorbide mono nitrate (IMN) is effective to induce
cervical ripening and shorten the interval time between induction and delivery.
Research Questions:
Does vaginal administration of isosorbide mono nitrate (IMN) induce cervical ripening and
shorten the interval time between induction and delivery in women undergoing induction of
labor at term or post term with prelabor rupture of membrane?