Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass
Status:
Withdrawn
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The main objective of this study is to evaluate the efficacy of intravenous sodium nitrite
compared with placebo in reducing the occurrence of CSA-AK as diagnosed by KDIGO criteria
during the first 72 hrs after cardiac surgery in high-risk patients undergoing cardiac
surgery. Secondary objectives are to determine whether IV sodium nitrite achieves adequate
pharmacokinetics (PK) in patients undergoing cardiac surgery with the use of CPB.