Nitrites, Exercise, and Peripheral Arterial Disease
Status:
Completed
Trial end date:
2014-11-01
Target enrollment:
Participant gender:
Summary
The hypothesis of this proposal is that in subjects with PAD, regular consumption of a high
nitrate supplement which raises plasma nitrite, in conjunction with 12 weeks of supervised
exercise training at the limb ischemic threshold (SET) will produce a greater clinical
benefit (increases in COT and PWT) than placebo plus supervised exercise at the limb ischemic
threshold (PET).