Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

• Status: Not yet recruiting
• Trial end date: 2021-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

This pilot study aims to assess the feasibility, acceptability, and effectiveness of using nitrous oxide (N2O) sedation for intrauterine device (IUD) insertions for nulliparous adolescent and young adult women in a primary care clinic setting.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Boston Children's Hospital; Boston Children’s Hospital
• Collaborator: Praxair Distribution, Inc.
• Treatments: Nitrous Oxide

Criteria

Inclusion Criteria:

• nulliparous (no pregnancy of 24 weeks' duration or longer and not currently pregnant)

• adolescent females (14-24 years)

Exclusion Criteria:

• use of opioids, benzodiazepines, or marijuana within the past 24 hours

• failure to meet medical eligibility criteria for an IUD

• medical contraindications to NSAID use

• relative contraindications to N2O administration, including severe pulmonary disease, congenital heart disease, diseases associated with vitamin B12 deficiency, and sickle cell disease