Overview

Nivolumab, Ipilimumab, and Bicalutamide in Human Epidermal Growth Factor (HER) 2 Negative Breast Cancer Patients

Status:
Recruiting
Trial end date:
2025-04-01
Target enrollment:
Participant gender:
Summary
The goal of this protocol is to evaluate the safety and efficacy of an alternative systemic combination approach that omits or delays the use of chemotherapy in metastatic disease, while improving efficacy and durability of response. The approach combines two potentially effective and previously studied strategies: androgen receptor blockade and immune checkpoint therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Providence Health & Services
Collaborators:
Bristol-Myers Squibb
Memorial Sloan Kettering Cancer Center
Treatments:
Bicalutamide
Ipilimumab
Nivolumab