Overview

Nivolumab and AVD in Early-stage Unfavorable Classical Hodgkin Lymphoma

Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The aim of the trial is to improve first-line treatment for early unfavorable cHL by introduction of the anti-PD-1 antibody Nivolumab with a truncated standard chemotherapy (AVD). The primary objective is to show efficacy of the two experimental treatment strategies. Secondary objectives are to further evaluate efficacy, show safety and feasibility and perform correlative studies.
Phase:
Phase 2
Details
Lead Sponsor:
University of Cologne
Treatments:
Antibodies, Monoclonal
Dacarbazine
Doxorubicin
Liposomal doxorubicin
Nivolumab
Vinblastine