Overview

Nivolumab and Bevacizumab in Patients With Advanced and or Metastatic Hepatocellular Carcinoma

Status:
Terminated
Trial end date:
2019-07-02
Target enrollment:
Participant gender:
Summary
This is an open label, phase I study to test for maximum tolerated dose (MTD) or recommended phase II dose (RP2D) of the combination of nivolumab and bevacizumab. The study will use a 3+3 phase I study design using a fixed dose of nivolumab (240mg) and escalating doses of bevacizumab (1-10mg).
Phase:
Phase 1
Details
Lead Sponsor:
University of Utah
Collaborator:
Bristol-Myers Squibb
Treatments:
Bevacizumab
Nivolumab