Overview

Nivolumab and Oral Cyclophosphamide for R/R AML and HIgh Risk MDS

Status:
Suspended
Trial end date:
2023-02-01
Target enrollment:
Participant gender:
Summary
This is a phase II trial of nivolumab and low dose cyclophosphamide (CTX) when given in combination to patients with relapsed/refractory acute myeloid leukemia (AML) and higher-risk myelodysplastic syndrome (MDS) who are not eligible for or decline hematopoietic stem cell transplant. It includes a randomized pilot sub-study during stage 1.
Phase:
Phase 2
Details
Lead Sponsor:
Masonic Cancer Center, University of Minnesota
Treatments:
Antibodies, Monoclonal
Cyclophosphamide
Nivolumab