Overview

Nivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell Lymphoma

Status:
Withdrawn
Trial end date:
2020-06-12
Target enrollment:
Participant gender:
Summary
This is a pilot study investigating the role of nivolumab, a PD-1 inhibitor, in the treatment of advanced stage or relapsed/refractory NKTL. Patients who have received PD-1 inhibitors will be excluded from this study. Patients who have a complete response or good partial response to nivolumab during initial phase will continue to be treated with nivolumab. Patients who have a partial response, stable disease, and progressive disease to nivolumab during initial phase will be treated with the combination of nivolumab and GDP/L-asparaginase.
Phase:
Phase 1
Details
Lead Sponsor:
National Cancer Centre, Singapore
Collaborator:
Bristol-Myers Squibb
Treatments:
Asparaginase
BB 1101
Cisplatin
Dexamethasone
Dexamethasone acetate
Gemcitabine
Nivolumab