Overview

Non Invasive Cardiac Output Monitoring to Guide Goal Directed Fluid Therapy in High Risk Patients Undergoing Urgent Surgical Repair of Proximal Femoral Fractures

Status:
Completed
Trial end date:
2017-09-28
Target enrollment:
0
Participant gender:
All
Summary
Improving or maximising cardiac output in the perioperative setting through the use of goal directed fluid therapy has been shown to reduce complications and length of hospital stay in patients undergoing major abdominal surgery. The evidence for patients having surgery to repair a fractured neck of femur is less robust but many of these latter patients are elderly and often at high risk of complications. Patients undergoing surgery (including surgery for hip fracture) under spinal anaesthesia have not had access to goal directed fluid therapy because of the invasive nature of the existing monitoring technology such as oesophageal doppler. The availability of a non invasive cardiac monitoring device, the Clearsightâ„¢, now makes goal directed fluid therapy a possibility for this group of patients. This is a randomised controlled, observer blinded trial to assess the effects of goal directed fluid therapy in high-risk patients undergoing surgical repair of proximal femoral fractures. The aim of the trial is to test the hypothesis that maximising circulating volume intra-operatively with balanced crystalloid reduces post-operative morbidity in high-risk patients undergoing urgent surgical repair of proximal femoral fractures.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
York Teaching Hospitals NHS Foundation Trust
Criteria
Inclusion Criteria:

- Patients due to undergo urgent or emergency repair of a proximal femoral fracture who
have a Nottingham hip fracture score (NHFS) ≥ 5 i.e. patients who are regarded as
'high risk'.

Exclusion Criteria:

- Age < 50 years. Patients scoring 5 on the American Society of Anesthesiologists (ASA)
physical status classification Multiple injuries requiring operative management