Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain
Status:
Recruiting
Trial end date:
2022-02-01
Target enrollment:
Participant gender:
Summary
The long term goals of our research are to establish the best pharmacological treatment for
NAS and determine how pharmacologic treatment of NAS affects long-term developmental
outcomes. The objective of this application is to evaluate the effectiveness of clonidine as
a treatment for neonates with NAS, in a randomized clinical trial. Our central hypothesis is
that clonidine will effectively treat drug withdrawal manifestations in neonates.
Phase:
Phase 3
Details
Lead Sponsor:
Henrietta Bada University of Kentucky
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Adrenergic alpha-2 Receptor Agonists Central Nervous System Depressants Clonidine Molecular Mechanisms of Pharmacological Action Morphine Opiate Alkaloids Peripheral Nervous System Agents