Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
Flexible bronchoscopy (FB) is a fundamental procedure for the diagnosis and treatment of
respiratory diseases. Although midazolam is the recommended sedative agent by most
guidelines, propofol has gained popularity due a short recovery time, however, evidence to
propofol use for sedation during FB is scarce. There is little evidence about transcutaneous
CO2 pressure (PtcCO2) behavior among patients sedated with propofol when it is administered
by non-anesthesiologist and in combination with intravenous opioids for analgesia and cough
inhibition.
The investigators performed a randomized controlled trial to determine whether
non-anesthesiology-administered balanced-sedation with propofol was related to high values of
values of PtcCO2 compared with guideline-based sedation (midazolam and opioid). The
investigators included data from outpatients 18 years or older with an indication for FB in a
university hospital in northern of Mexico. Secondary outcomes were recuperation time, patient
satisfaction and adverse effects.