Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting Conditions
Status:
Completed
Trial end date:
2020-05-25
Target enrollment:
Participant gender:
Summary
Monocentric study of no pharmacokinetic interaction between chlorthalidone and losartan, with
an open, randomized, single-dose design with four periods, four sequences and crossover in
healthy volunteers, under fasting conditions, administered in fixed combination (Test product
of Laboratorios Silanes, SA de CV) against the individual components administered jointly and
separately (Higroton® 50, a product of Sandoz, SA de CV and Cozaar® , a product of
Schering-Plow, SA de CV)