Non-invasive Early Goal Directed Therapy in Colorectal Surgery: a Feasibility Study

• Status: Completed
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The Nexfin monitoring system offers a complete non-invasive approach to a continuously estimation of blood pressure, CI and PPV by means of finger-cuff based pulse contour analysis. Several clinical investigations have proven reliability and interchangeability of the Nexfin technology yielding acceptable results especially regarding the trending abilities. At present there is no evidence available, whether a early goal directed hemodynamic optimization protocol based on a completely non-invasive monitoring technology is able to reduce postoperative complication. Therefore, the aim of this single-center study is to compare the clinical outcome and postoperative complications of patients undergoing major colorectal surgery treated with standard of care or with a GDT protocol based on the Nexfin technology.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Schleswig-Holstein; University of Schleswig-Holstein
• Treatments: Dobutamine; Norepinephrine

Criteria

Inclusion Criteria:

• Major abdominal procedures

• Estimated duration ≥120 minutes

• High transfusion probability

• Anticipated blood loss ≥1000 ml

Exclusion Criteria:

• Patients less than 18 years old

• ASA I or IV classification

• Heart rhythm disorders

• Advanced peripheral artery occlusive disease

• Arteriovenous shunts concerning upper extremities

• Laparoscopic abdominal procedures