Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.
Status:
Terminated
Trial end date:
2016-01-16
Target enrollment:
Participant gender:
Summary
The combination of different analgesic drugs and/or analgesia techniques is part of the
standard management of postoperative analgesia. The analysis of the literature reveals a lack
of comparison of the associations of non-opioid analgesic (NOA) with morphine for
postoperative analgesia.
The objectives of this study are :
- comparing the morphine sparing effect of different combination of 3 NOA (paracetamol,
nefopam, ketoprofen) for postoperative analgesia.
- determining whether the morphine-sparing effect is associated with or without a
reduction in the incidence of morphine side effects.
- evaluating the effects of NOA on postoperative hyperalgesia.