Non-steroid Antiinflammatory Drugs to Heal Colles Fracture

• Status: Completed
• Trial end date: 2021-03-18
• Target enrollment: 0
• Participant gender: All

Summary

It is believed that some painkillers (NSAID drugs) slow bone healing but the knowledge is based only on experimental studies with animals whose results are automatically translated for humans. The purpose is to examine whether these drugs slow bone healing and what relationship there is between different bone examinations, scan for osteoporosis, bone marker laboratory tests, radiological controls and histology of newly formed bone under a microscope.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northern Orthopaedic Division, Denmark
• Collaborator: Aarhus University Hospital
• Treatments: Anti-Inflammatory Agents; Ibuprofen

Criteria

Inclusion Criteria:

• Patients giving written informed consent and authority

• Patients with Colles fracture who require surgery by means of an external fixation or type bridging with or without suture.

• Patients who clinically and radiographically are diagnosed for reposition and therefore require external fixation or type bridging with or without suture.

Exclusion Criteria:

• Patients who have been given adrenal cortex hormone.

• Patients who have been given non-steroid antiinflammatory drugs (NSAID).

• Patients who have not been giving written informed consent and authority.

• Patients who smoke more than 20 cigarettes daily.

• Patients who consume more than 14 drinks weekly.

• Lack of mental and physical ability to follow the directions according to the protocol.

• Medical contraindication to non-steroid antiinflammatory drugs.