Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty

• Status: Recruiting
• Trial end date: 2023-09-01
• Target enrollment: 0
• Participant gender: All

Summary

To find noninferiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss and serum concentration during primary total hip arthroplasty.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Liege
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• ASA physical status 1, 2 and 3 scheduled for primary total hip arthroplasty

Exclusion Criteria:

• Renal failure with serum creatinine level higher than 1,40 mg/dL

• Thromboembolic events in last 12 months before surgery

• Pregnancy

• Congenital or acquired coagulation diseases

• History of gastric surgery that could lead to malabsorption

• Diabetic gastro-paresis