Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound
Status:
Completed
Trial end date:
2020-09-18
Target enrollment:
Participant gender:
Summary
This study will use contrast echocardiography to assess the accuracy of a new non-invasive
imaging method for subharmonic aided pressure estimation (SHAPE) compared to simultaneously
acquired intra-cardiac pressures measured invasively during cardiac catheterization. This
study is designed to verify that contrast echocardiography using the SHAPE method, already
proven in a canine model and tested in a human pilot study can be used as a surrogate for
cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.
Phase:
Phase 2
Details
Lead Sponsor:
Thomas Jefferson University
Collaborators:
GE Healthcare National Heart, Lung, and Blood Institute (NHLBI)