Overview

Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)

Status:
Terminated
Trial end date:
2017-03-29
Target enrollment:
Participant gender:
Summary
The main goal of the study is to determine if bone marrow transplant (BMT) from a less specific pool of donors in combination with high dose cyclophosphamide can induce remission of refractory systemic lupus erythematosus.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborator:
Maryland Stem Cell Research Fund
Treatments:
Antilymphocyte Serum
Cyclophosphamide
Fludarabine
Fludarabine phosphate
Mycophenolic Acid
Tacrolimus
Thymoglobulin
Vidarabine