Overview

Norepinephrine Transporter Blockade, Autonomic Failure (NETAF)

Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Drug therapy for patients suffering from autonomic failure and neurogenic orthostatic hypotension are scarce and not effective. If left untreated, these patients have the highest risk of syncope, falls and fall-related injuries. The proposed study will determine the clinical benefit of a commercially available drug, atomoxetine, to reduce symptoms associated with neurogenic orthostatic hypotension in patients with autonomic failure.
Phase:
Phase 2
Details
Lead Sponsor:
Vanderbilt University
Vanderbilt University Medical Center
Collaborators:
New York University School of Medicine
NYU Langone Health
Treatments:
Atomoxetine Hydrochloride
Norepinephrine