Norepinephrine in Caesarian Section

• Status: Not yet recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion. In this trial, postspinal hypotension will be treated with norepinephrine. The main objective is to examine the pharmacodynamic and biochemical effect of norepinephrine both on mother and newborn.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Antwerp
• Treatments: Norepinephrine

Criteria

Inclusion Criteria:

American Society of Anesthesiologists classification (ASA)1 and 2 patients non-laboring and singleton pregnancy

Exclusion Criteria:

patients with cardiovascular comorbidities any kind of cardiac and peripheral vascular disease or diabetes history of coagulopathy contra-indication to spinal anesthesia allergic condition to vasopressors or local anesthetics total body weight under 50kg or above 100kg length under 150cm and over 180cm Body Mass Index (BM)I ≥ 32