Overview

Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma

Status:
Recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
This randomized phase 2 study will evaluate 2 novel immunotherapy combinations in which pembrolizumab is integrated with ramucirumab and paclitaxel in patients with advanced gastric and GEJ adenocarcinoma. A total of 58 patients will be enrolled to the study. Each arm will have 26 patients. Although the study has a randomized design, patients in both arms will receive study drug (pembrolizumab).
Phase:
Phase 2
Details
Lead Sponsor:
Harry H Yoon
Collaborators:
Mayo Clinic
Merck Sharp & Dohme Corp.
Treatments:
Albumin-Bound Paclitaxel
Paclitaxel
Pembrolizumab
Ramucirumab