Nutrients and Hormones: Effects in Boys With Disordered Growth

• Status: Completed
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of the study is to find out if patients with constitutional delay of growth have a mismatch between energy intake and utilization (as measured by doubly labeled water) and to compare the improvement in growth and energy balance between a group of boys treated with growth hormone (GH) alone versus those given GH plus added nutritional supplements for one year.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nemours Children's Clinic
• Collaborator: Genentech, Inc.
• Treatments: Hormones

Criteria

Inclusion Criteria:

• Boys 7-10 years old who are very short and below average in weight but otherwise healthy.

• Delay in skeletal maturation > 1 year.

Exclusion Criteria:

• Growth hormone deficiency

• Chronic illness

• Participation in high endurance athletics