O6-Benzylguanine and Topical Carmustine in Treating Patients With Early-Stage IA-IIA Cutaneous T-Cell Lymphoma
Status:
Completed
Trial end date:
2014-04-08
Target enrollment:
Participant gender:
Summary
This phase I/II trial studies the side effects and best dose of carmustine when given
together with O6-benzylguanine and to see how well they work in treating patients with stage
IA-IIA cutaneous T-cell lymphoma. Drugs used in chemotherapy, such as carmustine, work in
different ways to stop the growth of cancer cells, either by killing the cells or by stopping
them from dividing. O6-benzylguanine may help carmustine work better by making cancer cells
more sensitive to the drug. Giving O6-benzylguanine with carmustine may kill more cancer
cells.