OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
Patients undergoing surgery (thyroidectomy and hysterectomy) will postoperatively receive
oxycodone intravenously (IV) as pain management with morphine as an escape medicine, if there
is insufficient pain relief with oxycodone. Patients' pain and side effects will be
registered and after 24 hours they will answer a questionnaire. All included patients will be
genotyped accordingly to CYP2D6 and relevant single nucleotide polymorphisms (SNPs), and
measures of plasma levels of oxycodone will be performed.