Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma
Status:
Completed
Trial end date:
2018-05-14
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. It is not yet known whether radiation therapy combined with chemotherapy is more
effective than radiation therapy alone in treating patients with low-grade glioma.
PURPOSE: Phase II/III trial to evaluate observation and to compare the effectiveness of
radiation therapy with or without combination chemotherapy in treating patients with
low-grade glioma.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Radiation Therapy Oncology Group
Collaborators:
Eastern Cooperative Oncology Group National Cancer Institute (NCI) North Central Cancer Treatment Group NRG Oncology Southwest Oncology Group