Occlusal Splints or Botulinum Toxin?

• Status: Completed
• Trial end date: 2019-03-10
• Target enrollment: 0
• Participant gender: All

Summary

73 patients with myofascial pain due to bruxism were included in this study. The patient were allocated into three groups. Group A was treated with occlusal splint, Group B was treated with botulinum toxin injection, Group C was treated with occlusal splint and botulinum toxin injection together. Temporomandibular Disorder Pain Screener (TMD-PS), Graded Chronic Pain Scale (GCPS), Oral Behavior Checklist (OBC), Jaw Function Limitation Scale (JFLS), Visual Analog Scale (VAS) by palpation of the chewing muscles were administered to all patients before treatment and at 6 months after treatment.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ankara University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; Salicylic Acid

Criteria

Inclusion Criteria:

• Patients older than 18 years with chronic myofascial pain

• More than 6 months with myofascial pain

• Diagnosis of myofascial pain according to the RDC/TMD

Exclusion Criteria:

• Patients having intracapsular TMD (disc displacement with or without reduction)

• A history of any treatment for bruxism, patients taking aminoglycosides

• Penicillamine

• Quinine and calcium blockers

• Pregnant or lactating mothers

• Having neuromuscular disorder (e.g. Orofacial tardive dyskinesia, Lambert-Eaton Syndrome, Myasthenia gravis)

• Having rheumatoid arthritis

• Having temporomandibular joint osteoarthrosis with radiographic signs

• History of previous joint surgery

• Patients who had undergone BTX treatment before or an allergy to BTX-A