Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial

• Status: Completed
• Trial end date: 2021-03-26
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to investigate whether octreotide, a medication used off-label to treat chylothorax, has a direct effect on human lymphatic drainage. To study the effects of octreotide, the researchers conducted a pre-clinical experiment using human lymphatic vessels mounted in a myograph chamber and a clinical experiment in which a double-blinded, randomized, cross-over trial wass conducted in 16 healthy adults. The results of the study will be used to determine the role of octreotide in the treatment of chylothorax and other lymphatic disorders.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Collaborators: Bispebjerg Hospital; University of Aarhus
• Treatments: Octreotide

Criteria

Inclusion Criteria:

• Healthy

Exclusion Criteria:

• No daily medication (except birth control), or allergies towards contrast agents.