Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome
Status:
Recruiting
Trial end date:
2036-01-20
Target enrollment:
Participant gender:
Summary
This protocol includes 2 independent studies. Both studies are multicenter studies,
evaluating different therapeutic approaches in two different populations of patients:
- Study 1, a randomized phase-II study evaluating the efficacy of Intra-Arterial
Chemotherapy (IAC) with melphalan and topotecan versus melphalan alone, both in
association with ophthalmologic treatments.
- Study 2, a minimally invasive interventional study evaluating the results on visual
function following reference treatment with intravenous (IV) chemotherapy in association
with ophthalmologic treatments.