Ocular-hypertensive Response to Topical Steroids in Children After Bilateral Strabismus Surgery

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the effects of topical (Rimexolone versus Dexamethasone) on the IOP in children under 13 years of age who underwent bilateral strabismus surgery, and to compare the effects of topical (Rimexolone versus Fluorometholone) on the IOP in the children under 13 years of age who underwent bilateral strabismus surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Fluorometholone; Rimexolone

Criteria

Inclusion Criteria:

• Children younger than 13 years of age.

• Children who underwent bilateral recession strabismus surgeries.

• Preoperative IOP of 21.00 mmHg or less, with a cup-disc ratio of 0.3 or less.

• The absence of systemic disease and ocular disease (apart from strabismus) in both eyes.

• Children who can comply with the IOP measurements using the Tono-Pen®, as no type of anesthesia will be used, except for the topical anesthesia.

Exclusion Criteria:

• Patients that are 13 years of age or older.

• Children who need resection muscle surgeries, surgeries for the vertical, or the oblique muscles.

• Preoperative IOP of more than 21.00 mmHg, or a cup-disc ratio of more than 0.3

• Family history of glaucoma or high myopia.

• A history of steroid usage in the past year.

• Failure to comply with IOP measurements or the follow-up schedule.