Overview

Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to investigate the efficacy of olanzapine as compared to neurokinin-1 receptor antagonists (NK1-RAs) in the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients with gynecologic malignancies receiving single day outpatient chemotherapy (carboplatin and paclitaxel) every 3 weeks.
Phase:
Phase 3
Details
Lead Sponsor:
University of Michigan Rogel Cancer Center
Treatments:
Dexamethasone
Fosaprepitant
Neurokinin-1 Receptor Antagonists
Olanzapine
Ondansetron
Prochlorperazine