Overview

Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects

Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
This study is a single arm, multi-centre phase II study of olaparib and bevacizumab combination therapy in subjects with relapsed small cell lung cancer (SCLC) as a second or third line (systemic) therapy. Subjects will receive olaparib and bevacizumab combination therapy. The arm is composed of 28 subjects. Olaparib 300 mg bid per os every 12 hours administered each cycle day and bevacizumab 15 mg/kg via IV administered on Day 1 of every cycle for every 3 weeks. One cycle consists of 21 days.
Phase:
Phase 2
Details
Lead Sponsor:
Keunchil Park
Se-Hoon Lee
Collaborators:
AstraZeneca
Roche Pharma AG
Treatments:
Bevacizumab
Olaparib