Overview

Omega-3 Fatty Acid-Based Parenteral Nutrition Improves Postoperative Recovery for Cirrhotic Patients With Liver Cancer

Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
0
Participant gender:
All
Summary
The safety and efficacy of ω-3 fatty acid in patients with liver cancer followed hepatectomy is not known. This study provided evidences that ω-3 fatty acid-based parenteral nutrition improved postoperative recovery for cirrhotic patients with liver cancer underwent hepatectomy..
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Huazhong University of Science and Technology
Criteria
Inclusion Criteria:

- The cirrhotic malnourished patients who were diagnosed as liver cancer preoperatively
and underwent hepatectomy were consecutively enrolled.

Exclusion Criteria:

- Contraindication for hepatectomy, including gastrointestinal hemorrhage, severe
hemorrhagic disorders, explicit acute nonspecific infectious lesion, overt ascites,
Child-Pugh Score C, indocyanine green retention rate at 15min (ICGR15)>30%(12), serum
hepatitis B virus (HBV)-DNA>126 copies/ml and serum alanine aminotransferase (ALT) >
2×ULN, serum triglycerides>2.0 mmol/L, circulatory shock, stroke, acute myocardial
infarction, renal failure, coma of unknown cause

- Pregnancy

- Age of<18y or>75y

- Performed intraoperative ablation

- Unresectable tumor during operation

- Allergic reactions against fish or egg proteins