Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
Status:
Completed
Trial end date:
2017-12-22
Target enrollment:
Participant gender:
Summary
This study evaluates the analgesic effect of Omnitram and tramadol during concurrent
administration of paroxetine. Paroxetine administration is expected to diminish the analgesic
effect of tramadol, but not Omnitram. Each participant will receive paroxetine before and
during treatment with Omnitram, tramadol, and placebo.
Phase:
Phase 1
Details
Lead Sponsor:
Syntrix Biosystems, Inc.
Collaborators:
DF/Net Rearch ITT Research Institute PRA Health Sciences