Overview

Ondansetron Versus Aprepitant Plus Ondansetron for Emesis

Status:
Completed
Trial end date:
2015-05-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to compare the effectiveness of receiving a combination of ondansetron and aprepitant to receiving ondansetron alone in helping to prevent nausea and/or vomiting in patients with Acute myeloid leukemia (AML) or high-risk (HR) Myelodysplastic syndromes (MDS) who are receiving cytarabine. The safety of this drug combination will also be studied.
Phase:
Phase 2
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Aprepitant
Fosaprepitant
Ondansetron