Opioid Effects on Cognitive Function Following Colonoscopy

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the effects of fentanyl and alfentanil on postprocedural cognitive function in elective endoscopy.

150 patients will be enrolled in the study. Patients meeting eligibility criteria will be randomly allocated to three groups.

The patients in Group A will be given propofol and alfentanil. The patients in Group F will be given propofol and fentanyl. Group P is designated as the control group and the patients will be given propofol for sedation.

Awareness, vital signs and pain will be evaluated. Side effects will be recorded. Patient and endoscopist satisfaction will be evaluated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Perihan Ekmekçi
• Treatments: Alfentanil; Fentanyl; Propofol

Criteria

Inclusion Criteria:

• Ages between 18-65

• American Society of Anesthesiologists classification I-III

• Patients scheduled to undergo elective colonoscopy or endoscopy and colonoscopy

Exclusion Criteria:

• Patients younger than 18 or older than 65

• Mini mental test score < 26

• APAIS (The Amsterdam Preoperative Anxiety and Information Scale) >10

• Serious systemic disease

• Neuropsychiatric disorder

• Chronic alcohol abuse

• Morbid obesity

• History of anesthesia in the last 7 days

• Known allergy to study drugs