Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration

• Status: Completed
• Trial end date: 2012-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine weather remifentanil induced swallowing difficulties increase risk for pulmonary aspiration.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Region Örebro County
• Treatments: Remifentanil

Criteria

Inclusion Criteria:

• 18 - 40 year old healthy volunteers from both sexes.

• Have signed and dated Informed Consent.

• Willing and able to comply with the protocol for the duration of the trial.

Exclusion Criteria:

• Pharyngoesophageal dysfunction

• Anamnesis of pharyngoesophageal dysfunction

• Known history of cardiac, pulmonary or neurological disease

• Ongoing medication

• Allergies to or history of reaction to naloxone, remifentanil, fentanyl analogues or other ingredients

• History of reaction to products containing human albumine

• Pregnancy or breast feeding

• BMI > 30

• Previous participation in a medical clinical trial where opioid has been used or have during last 30 days participated in any other medicinal clinical trial or in a trial where follow-up in not completed