Opioid Maintenance Medications Comparison Study

• Status: Completed
• Trial end date: 1998-06-01
• Target enrollment: 0
• Participant gender: All

Summary

A 17 week, double-blind, randomized, parallel group, four arm design outpatient study comparing LAAM, buprenorphine and two dose levels of methadone for the treatment of opioid dependence.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Treatments: Buprenorphine; Methadone

Criteria

Inclusion

• age 21 to 55 years

• diagnosis of opioid dependence by criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)

• evidence of recent opioid use on toxicologic screening

Exclusion

• serious medical or psychiatric illness requiring long-term medication

• positive pregnancy test