Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic Cholecystectomy

• Status: Not yet recruiting
• Trial end date: 2025-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Opioid sparing analgesia: Continuous intraoperative infusion of dexmedetomidine versus lidocaine for laparoscopic cholecystectomy, a randomized double-blind clinical trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexmedetomidine; Lidocaine

Criteria

Inclusion Criteria:

• Patient's status ASA status-I and II.

• Patients age above 18 years old.

• Patients scheduled for laparoscopic cholecystectomy.

Exclusion Criteria:

• Patient refusal.

• Patients with known allergy to dexmedetomidine or lidocaine.

• Patients with significant hepatic dysfunction.

• Patients with severe renal disease.

• Patients with chronic pain.

• Regular use analgesics, antidepressants or opioids in last month.

• Any known convulsive disorder.

• Significant heart disease.

• Morbid obesity (BMI>35).

• Patients with autoimmune disease

• Patients on corticosteroid therapy

• Pregnancy

• Breast feeding

• Woman under hormonal treatment