Opioid Sparing Anesthesia in Cervical Spine Surgery

• Status: Recruiting
• Trial end date: 2024-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Evangelismos Hospital
• Collaborator: Aretaieion University Hospital
• Treatments: Ketamine; Lidocaine; Remifentanil

Criteria

Inclusion Criteria:

• Adult patents

• American Society of Anesthesiologists (ASA) class I-III

• elective spine surgery

Exclusion Criteria:

• body mass index (BMI) >35 kg/m2

• contraindications to local anesthetic administration

• systematic use of analgesic agents preoperatively

• chronic pain syndromes preoperatively

• neurological or psychiatric disease on treatment

• pregnancy

• severe hepatic or renal disease

• history of cardiovascular diseases/ arrhythmias/ conduction abnormalities

• bradycardia(<55 beats/minute)

• drug or alcohol abuse

• language or communication barriers lack of informed consent