Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Opioids are frequently prescribed for chronic low back pain (CLBP). Psychiatric illness, such
as high levels of depression and anxiety symptoms, is a common co-occurrence in chronic pain
patients (and is termed comorbid negative affect [NA]). The purpose of the study is to
determine whether CLBP patients with either a high vs. a low or moderate degree of NA have
different pain relief responses to oral opioids.
Phase:
Phase 4
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborators:
Arthritis Foundation National Institute on Drug Abuse (NIDA)