Optimal Albuterol Regimens for Acute Asthma Exacerbations: DBRCT Pilot Study
Status:
Completed
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Our overall objective is to model a pediatric Acute Asthma Clinical Decision Rule (ADR) for
personalized medicine by identification of treatment-response phenotypes that are important
determinants of outcome. The Specific Aim of this study is to determine the feasibility of
this approach by enrolling a pilot cohort of 16 participants in this DBRCT of 4 different
albuterol treatment regimens, 2 of which will use 10mg/hr and 2 of which will use 25mg/hr.
Within these dosages there will be a pulsed-treatment regimen and a continuous regimen.
Phase:
N/A
Details
Lead Sponsor:
Vanderbilt University Vanderbilt University Medical Center