Optimal Bowel Preparation Regimen in Patients With Colorectal Surgery

• Status: Unknown status
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The study compares the efficacy of bowel cleansing between the standard preparation (2 L polyethylene glycol electrolyte solution, 2 L PEG-ELS), low-volume preparation (10 mg bisacodyl plus 2 L PEG-ELS) and high-volume preparation (4 L PEG-ELS) in patients with previous colorectal resection.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shandong University
• Treatments: Bisacodyl

Criteria

Inclusion Criteria:

• All adults (18< age<75years) referred for surveillance colonoscopy with a history of colorectal resection for Colorectal cancer (CRC).

Exclusion Criteria:

• severe comorbidities (e.g. congestive heart failure and severe kidney disease)

• abdominal and pelvic surgery other than colorectal resection for the cause of CRC.

• severe colonic stricture or obstructing tumour

• dysphagia

• compromised swallowing reflex or mental status

• significant gastroparesis or gastric outlet obstruction

• known or suspected bowel obstruction or perforation

• severe chronic renal failure (creatinine clearance<30 ml/min

• severe congestive heart failure (New York Heart Association class III or IV)

• uncontrolled hypertension (systolic blood pressure>170 mm Hg, diastolic blood pressure>100 mm Hg)

• inflammatory bowel disease or megacolon

• dehydration

• disturbance of electrolytes

• pregnancy or lactation

• haemodynamically unstable

• unable to give informed consent.