Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mg
Status:
Completed
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
This study evaluates the side effects of dose escalation in the treatment of donepezil 23mg
for patients with Alzheimer's disease. Investigators randomly divide participants into three
groups according to the dose escalation method; no titration, 15mg of donepezil for a month
before escalation to 23mg, and alternating of 10mg and 23mg for a month before escalation to
23mg.
Phase:
Phase 3
Details
Lead Sponsor:
Asan Medical Center
Collaborators:
Chung-Ang University Dong-A University Eisai Inc. Myongji Hospital Seoul National University Bundang Hospital Seoul St. Mary's Hospital