Overview Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer Status: RECRUITING Trial end date: 2035-12-01 Target enrollment: Participant gender: Summary A companion platform trial to test novel targeted agents based on the patient's tumor profile.Phase: PHASE1 Details Lead Sponsor: Australian & New Zealand Children's Haematology/Oncology GroupCollaborators: C17 CouncilChildren's Cancer Institute Australia (CCIA)Kazia Therapeutics LimitedMedical Research Future FundThe Hospital for Sick ChildrenTreatments: IrinotecanTemozolomide