Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the Pregnancy
Status:
Unknown status
Trial end date:
2017-08-01
Target enrollment:
Participant gender:
Summary
To determine the optimal time for the Tenofovir treatment of anti-Hepatitis B Virus (HBV)
during the pregnancy among women with chronic HBV infection and high HBV DNA load. This is a
randomized, open-label, three-arms, parallel-controlled clinical trial. Pregnant women with
high HBV load and normal liver function will be treated with tenofovir during the middle or
late stage of pregnancy, started from 24th gestational week, 28th gestational week and 32th
gestational week through 1 month postpartum, respectively. The HBV DNA load at 40th
gestational week of mothers, the intrauterine HBV infection rate of infants will be compared
across the three groups.
Phase:
N/A
Details
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University