Optimization of Serum Phosphorus Level and Weaning From Mechanical Ventilation

• Status: Recruiting
• Trial end date: 2023-02-28
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to test the impact of serum phosphorus level optimization on weaning from mechanical ventilation in adult ICU patients in Alexandria University Hospitals.

The main questions it aims to answer are:

• Does serum phosphorus level optimization affect the duration of mechanical ventilation?

• Is serum phosphorus level optimization associated with successful weaning from mechanical ventilation?

In critically ill patients, phosphorus supplementation is done using Sodium glycerophosphate pentahydrate solution.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alexandria University

Criteria

Inclusion Criteria:

• Adult mechanically ventilated ICU patients.

• Age ≥ 18 years.

Exclusion Criteria:

• Age <18 years

• Hypernatremia

• Permanent or prolonged mechanical ventilation

• Hyperphosphatemia which might occur in the following conditions:

• Chronic kidney disease and end stage renal disease

• Parathyroid disorders

• Cancer patients at risk of tumor lysis syndrome

• Immobility

• Body weight < 50 Kg