Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

• Status: Recruiting
• Trial end date: 2023-01-30
• Target enrollment: 0
• Participant gender: All

Summary

The overall goal of this research is to improve perioperative pain treatment, decrease post-operative opioid consumption, diminish opioid related side effects, and reduce postop opioid prescribing (and hence opportunity for diversion, abuse, addiction, and fatal overdose).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Duke University
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Anesthetics; Fentanyl; Hydromorphone; Methadone; Morphine; Sufentanil

Criteria

Inclusion Criteria

• Age 18-65 years Undergoing general anesthesia and moderately painful ambulatory surgery with anticipated postop stay of < 24 hours

• Signed, written, informed consent

Exclusion Criteria

• History of liver or kidney disease.

• Females who are pregnant or nursing.

• Chronic opioid use (e.g. preoperative daily use of methadone, fentanyl transdermal patches, or ≥ 3 oxycodone pills)